深圳大学西丽校区

学术讲座

【材料学院】学术报告四十一:Study Bacteria Adhesion and Biofilm Development: Modelling and Experimental

2018年12月21日

报告主题:Study Bacteria Adhesion and Biofilm  Development: Modelling and Experimental Characterisation

报告嘉宾:Jinju Chen教授英国纽卡斯尔大学 

  间:20181224日(周下午15:00-16:30

  点:材料学院537会议室

 报告人简介

Dr  Jinju (Vicky) Chen is a Senior Lecturer (Associate Professor) in Biointerface  Engineering within School of Engineering at Newcastle University (Russell Group)  in United Kingdom. She established and led a research team with two ongoing  post-doctoral research fellows (funded by EPSRC) and 9 PhD students.  She is a  Strategic Co-I and theme leader in Flow and Biomechanics for A New Frontier in  Design: The Simulation of Open Engineered Biological Systems, one of the only  five prestigious Frontier Awards (£5.56 millions) funded by EPSRC. She is also  the PI for the ongoing EPSRC funded strategic equipment grant (£0.49M).  

She  completed her PhD thesis within 2 years and 9 months on nanomechanics and  fracture mechanics of thin films. Then, she started working on cell mechanics,  tissue engineering, bacteria physics, antimicrobial surfaces, biofilms mechanics  and biofilm modelling.  She is the Principal Editor of Journal of Materials  Research and Guest Editor for Special Issue "Physics and Mechanics of Biofilms "  in Processes.  She is also an Editorial Board Member for Scientific Reports  (Nature Publishing Group) in Biological Physics. She has given over 10 invited  talks at major international conferences. She is also the Chair of Tyne and Wear  Materials Society. She also organized and chaired over 10 sessions at major  international conferences. She is also the external PhD examiner for the  world-leading overseas Universities. She regularly reviews research grants for  both UK research councils, French National Research Agency, Czech Republic  Science Foundation and Singapore Research Council.  Her web profile can be found  below.

 

报告摘要

Bacteria-materials  interactions are important for biofilm formation. The formation of biofilms has  great impacts on a wide range of industries such as biomedical industries,  marine industries and water industries. Therefore, it is important to understand  how materials surface properties will affect bacteria attachment on surfaces and  biofilm formation. In this study, the extended Derjaguin-Landau-Verwey-Overbeek  (XDLVO) theory has been adopted to model how surface roughness and surface  topography of materials as well as appendages of bacteria will affect bacteria  attachment to material surfaces. These agree with experimental measurement.  However, when it comes to nanostructured antimicrobial surface, the so-called  surface roughness effect reinforced XDLVO model is not applicable which will be  addressed in this talk.  

In  addition, an individual based model has also been developed to predict biofilm  formation, and flow induced biofilm deformation, erosion and streamer formation.  In this multiphysics computational model, bacteria growth, division, decay,  mechanical contact between bacteria cells and adhesion between the  bacteria-extracellular polymer substance, as well as flow shear force were  implemented.

 

欢迎有兴趣的师生前来参加!